By Giuseppe Perale, Jöns Hilborn
Bioresorbable Polymers for Biomedical purposes: From basics to Translational Medicine offers readers with an outline of bioresorbable polymeric fabrics within the biomedical box. an invaluable source for fabrics scientists in and academia, providing details at the basics and issues, synthesis and processing, and the medical and R and D functions of bioresorbable polymers for biomedical applications.
- Focuses on biomedical functions of bioresorbable polymers
- Features a finished diversity of issues together with basics, synthesis, processing, and applications
- Provides balanced insurance of the sphere with contributions from academia and industry
- Includes medical and R and D functions of bioresorbable polymers for biomedical applications
Read or Download Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine PDF
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Additional resources for Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine
The degree of deacetylation of typical commercial chitosan is usually between 70% and 95%, and the molecular weight is between 10 and 1000 kDa (George, 2006). The properties, biodegradability, and biological role of chitosan are dependent on the relative proportions of N-acetyl-D-glucosamine and D-glucosamine residues (Huang, 2005). Production of chitosan is inexpensive, easy, and can provide additional control over chitosan ﬁnal properties. In addition, the chitosan molecule has amino and hydroxyl groups that can be modiﬁed chemically, providing a high chemical versatility.
Other typical products for this kind of biomaterial are absorbable sutures, bone fracture ﬁxation devices, and tendon or ligament ﬁxation tacks. Biologically active (bioactive) materials that are capable of stimulating the surrounding tissue and enhance tissue growth and regeneration have been developed and include Bioglass (Hench, 1971), natural polymer (used “as cast”), and also polymer-incorporating selected proteins and growth-stimulating factors. Biodegradable polymers are widely used and investigated to produce scaffolds for engineering (Agrawal, 2001; Kellom€aki, 2000), simple sutures, ﬁxation screws, gauze strips, and bone grafts.
3 Extrusion and ﬁber manufacturing In extrusion, a polymer melt is pumped through a shaping die and formed in a proﬁle such as a ﬁlm, a ﬁber, a hollow ﬁber, or a sheet. There are two kinds of approach: ram and screw extruders. Ram extruders adopt a positive displacement pump based on pressure, the volume is reduced, the ﬂuid is moved, and the pressure rises. Screw extruders use a viscosity pump based on the pressure gradient and ﬂuid deformation. 1 Schematic parts of a single-screw extruder. , Stamboulis, A.